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INQUIRY FOR SUITABLE LOCATIONS FOR A DRILLING REGIME AT AN UPSLOPE ROCKY KNOLL OF LAWU ESTATE, WESTERN BYPASS, MINNA, NIGERIA

Background: A client requested that the study group help determine locations that would be suitable for a drilling regime at his lot, located at an upslope rocky knoll of Lawu Estate, Minna, Nigeria. Aim: The aim of this study is to carry out a purpose-specific survey to pinpoint the best locations in a built-up property at the upmarket Lawu Estate that would be suitable for a drilling regime targeted for household consumption. Methods: The study area was reconnoitered by the survey crew in order to georeference the locations that would be occupied for the vertical electrical sounding survey in the 30 m x 20 m lot. Owing to the extensive build-up at this lot, only a four-point traverse along the 30-metric dimension traverse of the frontage of the building was demarcated in the northeasterly direction, thereby limiting the desire of the survey crew to define an appropriate survey grid. The data-acquisition pattern at the 4 x 1 survey stations of the frontage-traverse of the lot followed the “traditional” sequence of Schlumberger array layout measurements, whence the survey crew progressed with current-electrode spacing either end of a survey point located at this frontage-traverse targeting a maximum survey depth of 100 m. Result: The acquired vertical electrical-sounding data set for this study was recorded on purpose-specific data sheets. Discussion: Based on empirical rules-of-thumb procedures for interpreting vertical electrical sounding data at the Nigerian Basement Complex geological province, “assured” groundwater location and “strongly aquiferous” location, deductive inferences were drawn with regards to only vertical electrical sounding Station 4. Conclusion: Thus, it is recommended that VES Station 4 be exploited in the planned drilling program of the client, especially since this survey point checks off 100 percent of the constraints imposed by the rules-of-thumb interpretation procedures.
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FROM AIR FORCE TO HYPERSONIC FUTURE: ÉLCIO GERÔNIMO DE OLIVEIRA'S JOURNEY IN BRAZILIAN AEROSPACE DEVELOPMENT (ENGLISH VERSION)

Introdução: A entrevista com Élcio Gerônimo de Oliveira, conduzida pelo repórter Luis, apresenta a trajetória profissional de um pesquisador brasileiro com experiência na Força Aérea Brasileira e no meio acadêmico, com foco em sistemas espaciais e veículos hipersônicos. Objetivos: Documentar a carreira e contribuições de Élcio para o desenvolvimento aeroespacial brasileiro, destacando sua transição da carreira militar para a acadêmica e sua participação em projetos estratégicos, especialmente o projeto 14X. Métodos: A entrevista foi estruturada em blocos temáticos, abordando a carreira militar, a experiência acadêmica e, com maior detalhamento, o envolvimento no projeto do veículo hipersônico 14X. Foram realizadas perguntas abertas, permitindo ao entrevistado compartilhar sua experiência e conhecimento técnico. Resultados: Élcio descreveu sua progressão na Força Aérea Brasileira, desde pesquisador até vice-chefe da Diretoria de Espaço, destacando o desenvolvimento de veículos lançadores, sistemas de navegação inercial e o projeto SARA. Relatou sua transição para a carreira acadêmica, incluindo sua experiência como professor na Universidade de Luleå, na Suécia. Élcio detalhou sua coordenação no projeto 14X, um veículo hipersônico que alcançou Mach 7, com perspectivas de atingir Mach 10. Discussão: A entrevista revela a importância da cooperação internacional e da transferência de tecnologia, exemplificada pela doação do primeiro laboratório de hipersônica do Brasil. Evidencia também os desafios técnicos na construção de veículos hipersônicos e o potencial dessas tecnologias para aplicações militares e civis. Conclusão: A carreira de Élcio Gerônimo de Oliveira exemplifica a contribuição brasileira para pesquisa aeroespacial avançada, demonstrando a capacidade nacional de desenvolver tecnologias estratégicas como veículos hipersônicos, apesar das limitações de recursos, e apontando possibilidades futuras para o transporte e exploração espacial.
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THE REVOLUTION IN AMERICAN PUBLIC HEALTH POLICY: PETROLEUM-BASED DYES AND THE CHRONIC DISEASE EPIDEMIC

Background: The American food regulatory landscape has historically been influenced by industry interests, resulting in the widespread use of petroleum-derived synthetic food dyes banned in European countries. Chronic disease rates in American children have increased from 3% in the 1960s to approximately 60% currently, with annual healthcare costs reaching $1 trillion. The appointment of Robert F. Kennedy Jr. as Secretary of Health and Human Services marks a paradigmatic shift toward transparency and industry accountability in food safety regulation. Aim: This forum analysis examines Kennedy Jr.'s revolutionary approach to food safety regulation, particularly his confrontational stance against petroleum-based food additives exemplified by his statement, "if they want to eat petroleum, they should add it themselves at home" and evaluates the broader implications for American public health policy and global regulatory standards. Methods: Critical analysis of Kennedy Jr.'s public policy statements, examination of epidemiological data trends, and evaluation of proposed regulatory frameworks through content analysis of official speeches and policy declarations from the Department of Health and Human Services. Results: Kennedy Jr.'s administration targets the systematic elimination of synthetic food dyes through industry partnerships, scientific transparency initiatives, and restoration of rigorous research standards. His confrontational rhetorical approach, compared to Mike Tyson's boxing style, has generated unprecedented industry cooperation with food companies "calling almost daily" seeking compliance guidance. The strategy combines voluntary industry agreements with open-source information databases and enhanced FOIA access. Discussion: This confrontational rhetoric represents unprecedented directness in health policy communication, challenging decades of established regulatory practices. The approach prioritizes scientific transparency over diplomatic language, generating both media attention and voluntary industry engagement that traditional regulatory pressure failed to achieve. Conclusions: Kennedy Jr.'s revolutionary stance may establish new global standards for food additive oversight, prioritizing public health over commercial interests through evidence-based policymaking and industry accountability measures. This paradigm shift from reactive to preventive regulatory models could influence international food safety governance and restore American leadership in global health policy.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Araucária - Scientific Association.
  • Language of Publication: ENGLISH / PORTUGUESE*
  • *Year that the Journal started accepting manuscripts in Portuguese: 2020
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 06/07/2025.

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STATISTICAL VALIDATION OF TRIPLE COLOCALIZATION ANALYSIS

Background: in the last decades, colocalization analysis of fluorescently tagged biomolecules has proven to be a powerful approach to studying functional relationships between these biomolecules. However, in many cases, to give this analysis a biological meaning, colocalization coefficients must be tested statistically, comparing them with the colocalization expected by chance. Aim: It addressed the statistical significance of triple colocalization to distinguish real triple colocalization and classify different triple signal scenarios. Methods: we use biological and generated images of triple signal scenarios to contrast seven independent statistical facts with independent statistical tests. Three of these tests correspond to pairwise relationships (double scrambling tests), and the others correspond to triple relationships: single scrambling tests (red, green, and blue scrambling) and the triple scrambling test. The analysis and methodology proposed can be reproduced using the application developed in our laboratory. Results: In the study approach, we found true triple relationships ignored by using traditional methods of computing the statistical significance, while we could reinterpret cases of not significant triple colocalization wrongly considered as significant by traditional methods. Discussion: single scrambling tests can reveal significant triple colocalization for low levels of triple co-occurrence, even when all pairwise relationships were exclusion relationships. Moreover, on the other hand, single scrambling tests can reveal the absence of a significant triple colocalization for high levels of triple co-occurrence, even when all pairwise relationships were significant colocalization. Conclusion: all scrambling tests are useful to classify a specific scenario of a triple relationship. Dynamics like mitosis can be distinguished into their phases by triple signal relationships using these 7 independent statistical tests.
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UNRAVELING THE COMPLEXITIES OF CARDIOVASCULAR MEDICINE: A CONVERSATION WITH DR. PETER MCCULLOUGH (EXTENDED EN-US VERSION)

Background: This interview covers Dr. Peter McCullough’s medical career, experience as an editor of medical journals, and his expertise in areas such as cardiomyopathy, myocarditis, and pericarditis. Aims: The primary aim is to understand Dr. McCullough’s perspectives on various medical topics, including his journey as a cardiologist, the importance of peer review, the phenomenon of Pheidippides cardiomyopathy, the differences between myocarditis and pericarditis, and the significance of ethical principles like the Nuremberg Code and the Declaration of Helsinki. Additionally, the interview aims to explore his concerns about censorship during the COVID-19 pandemic. Methods: The interview follows a question-and-answer format, with the interviewer posing questions to Dr. McCullough on various topics related to his medical career, research interests, and ethical considerations. Results: Dr. McCullough shares his insights on topics such as cardiomyopathy, myocarditis, and pericarditis, emphasizing the importance of peer review, identifying potential biases, and balancing scientific rigor with timely dissemination of findings. He also highlights the significance of the Nuremberg Code and the Declaration of Helsinki in ensuring informed consent and preventing coercion in medical research and treatment. Discussion: Dr. McCullough expresses concerns about censorship during the COVID-19 pandemic, which he believes impacted the ability of medical professionals to freely discuss and disseminate health-related information. He also discusses the potential role of COVID-19 vaccines in causing myocarditis and the need for transparent communication about treatment options and potential complications. Conclusion: The interview provides valuable insights from Dr. McCullough’s extensive medical experience and expertise, covering a range of topics from cardiovascular conditions to ethical principles and the challenges posed by censorship during the COVID-19 pandemic.
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ASSESSMENT OF SERUM SCLEROSTIN LEVEL AS A BIOMARKER ASSOCIATED WITH BONE DISORDERS IN Β-THALASSEMIA PATIENTS IN AL- NAJAF CITY, IRAQ

Background: β-thalassemia is a blood disorder in which the body does not make hemoglobin normally. Aim: To assess serum sclerostin in female patients with beta-thalassemia and compare with the healthy controls and to predict its complication associated with the bone pathophysiology, for designed improvement the lifestyle goodliness for these patients. Material and methods: Sixty-nine female beta-thalassemia (βT) patients (54 βT major and 15 βT Intermedia), aged 8-40 years who dependent on transfused blood, and 20 healthy controls were evaluated serum sclerostin, and was examined the relationship with hematological parameters RBC, Hb, PCV, WBC, PLT, BMI, splenic status, iron, and ferritin levels. The information of beta-thalassemia patients was collected and records by the questioner. Results: A significantly increased serum sclerostin level (mean 26.80±0.91) pg/ml was showed in βT patients compared with the healthy controls (10.03±0.68, p  smaller than  0.001) pg/ml. Furthermore, a significant decrease (p smaller than 0.05) of the sclerostin level was observed in β-thalassemia major compared to intermedia β-thalassemia patients. Serum sclerostin level revealed a significant increase in progress age; it is highest in the age group (30-40) year as compared with age group (8-18) and (19-29) year respectively. Sclerostin showed no associations with the RBC, Hb, PCV, and significantly positively correlated (p smaller than 0.05) with serum iron, ferritin levels, WBC, and PLT count. Significantly higher sclerostin levels in splenectomized and underweight groups were observed compared to unsplenectomized and normal-weight groups (p smaller than 0.05) of βT patients. Conclusions: Sclerostin plays an important role in beta-thalassemia patients and can serve as a biomarker associated with the bone pathophysiology and indicator to prevent the continuation of such serious diseases caused by iron overload in these patients.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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