Latest Edition Highlights (Issue 41)

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CHARACTERIZATION OF TICKS IN THE GRAN MENDOZA AREA, MENDOZA, ARGENTINA

Background: Vector-borne diseases are increasingly important because they are emerging and re-emerging. Of the 867 tick species reported worldwide, 10% (86 species) have public health implications; 58 parasitize dogs, and 12 have been documented in Argentina. Tick-borne agents are increasingly relevant in the Cuyo region, with implications for both public health and domestic animal health. In Mendoza, the Rhipicephalus sanguineus complex and Amblyomma tigrinum have been documented. Aim: This study aimed to determine whether one tick genus predominated over the other, compared with previous studies in the region. Methods: We collected ticks from dogs attending municipal vaccination campaigns and veterinary clinics in several departments of the Greater Mendoza area (Ciudad/Capital, Luján de Cuyo, Godoy Cruz, and Guaymallén). Specimens were preserved in 70% (v/v) ethanol in sealed containers until analysis. Identification was performed using a stereomicroscope and the taxonomic keys of Nava. Results: The highest number of ticks was obtained from Ciudad/Capital, followed by Luján de Cuyo, Godoy Cruz, and Guaymallén. A total of 439 specimens were collected and classified by genus, species, and sex. Of these, 94.46% (415 ticks) corresponded to the Rhipicephalus sanguineus complex, including 193 females (43.96%) and 222 males (50.5%). The remaining 5.48% (24 ticks) were identified as Amblyomma tigrinum, including 17 females (3.89%) and 7 males (1.59%). Discussion: These findings confirm the marked predominance of the Rhipicephalus sanguineus complex among ticks collected from dogs in the Greater Mendoza area.
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CARDIOVASCULAR RISK AND DIETARY HABITS IN TRANSGENDER ADULTS RECEIVING HORMONE THERAPY

Background: Transgender and gender-diverse individuals experience health inequities that may increase cardiometabolic risk. Gender-affirming hormone therapy has been associated with changes in body composition, lipid metabolism, and cardiovascular risk markers. However, limited evidence is available regarding dietary habits and cardiovascular risk profiles in transgender populations in Latin America. Objective: To evaluate cardiovascular risk factors and cardioprotective food consumption among transgender adults receiving gender-affirming hormone therapy. Methods: A quantitative, observational, descriptive, and cross-sectional study was conducted in transgender adults undergoing gender-affirming hormone therapy in Mendoza, Argentina. Eighty-seven participants completed surveys regarding sociodemographic characteristics, lifestyle habits, nutritional counseling, and consumption of cardioprotective foods. We assessed anthropometric indicators and biochemical parameters related to cardiovascular risk. Statistical analyses were performed using GraphPad Prism 8. Data were analyzed using Spearman correlation, the chi-square test, and the Mann-Whitney U test. Results: A high prevalence of modifiable cardiovascular risk factors was identified, including overweight, sedentary behavior, smoking, and low intake of cardioprotective foods. More than half of the participants had never received nutritional counseling. No statistically significant differences were observed between transgender women and transgender men in the evaluated anthropometric and biochemical variables. Nevertheless, significant correlations were identified between body mass index, waist circumference, waist-to-height ratio, and atherogenic lipid markers. Dietary quality showed limited associations with cardiovascular risk indicators, although higher dietary quality was positively associated with HDL cholesterol levels in transgender men. Conclusion: The study highlights the presence of multiple cardiovascular risk factors in transgender individuals receiving gender-affirming hormone therapy and emphasizes the importance of integrating nutritional assessment and cardiometabolic monitoring into comprehensive transgender healthcare. These findings support the need for inclusive nutritional interventions and longitudinal studies addressing cardiovascular health in transgender populations.
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DIET, SUPPLEMENTATION, PERFORMANCE, AND SUBJECTIVE EXPERIENCE IN MARATHON RUNNERS

Background: Nutrition strategies may influence marathon performance and runners’ subjective experience. Aims: To evaluate the association between dietary habits, supplement use, performance, and subjective experience in runners of the 2025 Mendoza International Marathon. Methods: A survey of 240 runners from the 2025 Mendoza International Marathon examined dietary habits, supplement use, performance, and subjective experience. Results: Nutritional counseling was linked to more favorable perceptions. Conversely, pre-race alcohol and excessive carbohydrates with poor hydration increased gastrointestinal complaints. Supplements showed no measurable performance or well-being benefits. Discussions: These findings suggest that pre-race nutritional behaviors may have a greater influence on runners’ subjective experience than supplement use.Conclusions: Nutritional guidance may improve race experience, whereas poor pre-race practices increase gastrointestinal complaints.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Mendoza University - Argentina | Araucária - Scientific Association (leaving).
  • Language of Publication: ENGLISH / PORTUGUESE* / SPANISH**
  • *Year the Journal started accepting manuscripts in Portuguese: 2020
  • *Year the Journal started accepting manuscripts in Spanish: 2026
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 18/09/2026.

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EVALUATION OF TNF-Α CONCENTRATION LEVEL IN PATIENTS INFECTED WITH HYDATID CYSTS IN AL-NAJAF HOSPITALS

Background: Human echinococcosis is a zoonotic disease caused by Echinococcus granulosus, the etiological agent of cystic echinococcosis (CE). Aim: This study aims to determine the epidemiological prevalence of Echinococcus granulosus in patients with hydatid cysts and evaluate serum TNF-α levels associated with echinococcosis, as well as the correlation between these levels and disease progression. Methods: Radiological examinations were performed to diagnose Echinococcus granulosus by identifying echinococcal cysts. The study included patients of all ages and both sexes from Al-Sader Medical City, Al-Hakeem General Hospital, Al-Haidarya General Hospital, and Al-Hayat Hospital. The study period was from October 2023 to the end of January 2024. Results: The mean TNF-α level in patients was 163.27 pg/ml, significantly higher than the mean level of 38.58 pg/ml in controls (p-value < 0.001). Conclusion: The prevalence of hydatid disease in Al-Najaf Al-Ashraf was found to be 33%. TNF-α levels are notably higher in patients with Echinococcus granulosus who are under 40 years of age compared to those over 40 years of age.
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TREATMENTS FOR ACUTE LYMPHOBLASTIC LEUKEMIA: A COMPARISON BETWEEN TISAGENLECLEUCEL AND CLOFARABINE

Background: Acute lymphoblastic leukemia (ALL) is a heterogeneous hematological malignancy predominantly affecting individuals under 20 years of age. Traditional chemotherapy, such as clofarabine, has shown efficacy; however, novel immunotherapeutic strategies like tisagenlecleucel (Kymriah®) have significantly altered the treatment paradigm. Aim: This study aimed to perform a comparative analysis of tisagenlecleucel, a CAR-T cell therapy, and clofarabine, a second-generation purine nucleoside analog, evaluating their mechanisms of action, therapeutic benefits, limitations, and clinical applicability across diverse patient populations. Methods: A systematic comparative evaluation was conducted, encompassing pharmacological characteristics, mechanisms of action, treatment protocols, efficacy, safety profiles, and clinical indications of both agents. The analysis considered pharmacokinetic and pharmacodynamic data and included patient demographic variables. Results: Tisagenlecleucel demonstrated high efficacy in refractory B-cell ALL, with durable responses and a blood half-life of 128 days, but with notable immune-related adverse effects such as cytokine release syndrome. Clofarabine, effective across a broader patient population, acts via multiple antitumor mechanisms but carries significant toxicity risks, including infection and sepsis. Discussion: The therapies present distinct clinical profiles: tisagenlecleucel offers targeted immunotherapy with high specificity but requires specialized infrastructure and management of immune toxicities. Clofarabine is more widely accessible and applicable, but is associated with conventional chemotherapy-related side effects. Treatment accessibility and cost differ markedly between the two. Conclusions: Therapy selection should be personalized based on patient-specific factors and institutional resources. Tisagenlecleucel is ideal for pediatric and young adult patients with relapsed/refractory B-cell ALL in CAR-T-capable centers, while clofarabine remains a viable option for broader ALL populations, particularly when genetic therapies are not feasible. Further research is needed to optimize therapeutic strategies and improve access to advanced treatments.
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THE ROLE OF THE MEDITERRANEAN DIET IN PREVENTING MALE INFERTILITY: AN INTERVIEW WITH DR. MIGUEL FORNES (US-EN VERSION)

Background: Dr. Miguel Fornes is a researcher at CONICET and director of the Andrological Research Laboratory of Mendoza, Argentina. His research focuses on how dietary fat excess and hypercholesterolemia affect sperm physiology and male fertility. Objectives: The primary objective of Dr. Fornes' research is to investigate the effects of a high-fat diet on sperm function, capacitation, acrosomal reaction, and fertilization. He aims to develop translational animal models to study these effects without using human subjects. Methods: Dr. Fornes and his team use rabbit models to induce hypercholesterolemia through a high-fat diet. They then study the physiology and function of sperm cells from these hypercholesterolemic rabbits. Key parameters analyzed include cholesterol content in sperm membranes, ability to undergo capacitation and acrosomal reaction, and fertilization capability. Results: The studies revealed that hypercholesterolemia caused by a high-fat diet leads to increased cholesterol levels in sperm. This interferes with the normal physiology of sperm cells. In particular, many sperm from hypercholesterolemic rabbits were unable to properly undergo the acrosomal reaction, a crucial step for successful fertilization of the oocyte. This suggests high-fat diets could contribute to male infertility. Conclusions: The research highlights the importance of diet and lifestyle on male reproductive health. Dr. Fornes recommends a balanced diet like the Mediterranean diet, rich in fruits, vegetables, and olive oil, to maintain healthy sperm function and fertility. Replacing animal fats with olive oil may help prevent hypercholesterolemia-related infertility. The findings have implications for dietary guidelines and clinical interventions to support male fertility.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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