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SEVENTY YEARS OF THE BRAZILIAN FEDERAL COUNCIL OF CHEMISTRY (1956–2026): INSTITUTIONAL TRAJECTORY, PRESIDENCIES, AND PERSPECTIVES FOR THE CHEMISTRY PROFESSION - EN

Background: In 2026, the CFQ/CRQ System turns 70 (Law No. 2,800/1956), overseeing a sector responsible for ~11% of industrial GDP, but it lacked a chronological reconstruction based on its own official primary records. Aim: To reconstruct the System's legal genesis, establish a documented official chronology of its presidencies, and discuss current regulatory challenges. Methods: Historiographical-descriptive documentary research based on normative sources and unprecedented access to the internal record "Galeria de Presidentes," provided by the CFQ Presidency Office in 2026. Results: Eight substantive presidencies and interim periods (1957–2026) were detailed, substantiating the interim exercise by Oscar Bergstron Lourenço (1963–1964) and Juvenal Dória's inauguration in 1964. The System now comprises 21 regional councils and over 230,000 registrants. The study identified under-documentation of Hebe Martelli's trajectory (the only female president) and an open divergence regarding the number of regional councils created in 1957. Discussion: Normative Resolution No. 36/1974 remains the milestone for professional attributions. Recent regulations revisit historical challenges, such as attributing competencies to hybrid curricula and establishing chemical safety as a public good, requiring anticipation of energy, materials, and digital transitions. Limitations: The chronology relies on institutional records that the authors did not independently audit against primary archives. Conclusions: Access to primary records consolidated the documentary memory of the System's seventy years, whose legacy lies in adapting the regulatory framework to technological transformations.
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CARDIOVASCULAR RISK AND DIETARY HABITS IN TRANSGENDER ADULTS RECEIVING HORMONE THERAPY

Background: Transgender and gender-diverse individuals experience health inequities that may increase cardiometabolic risk. Gender-affirming hormone therapy has been associated with changes in body composition, lipid metabolism, and cardiovascular risk markers. However, limited evidence is available regarding dietary habits and cardiovascular risk profiles in transgender populations in Latin America. Objective: To evaluate cardiovascular risk factors and cardioprotective food consumption among transgender adults receiving gender-affirming hormone therapy. Methods: A quantitative, observational, descriptive, and cross-sectional study was conducted in transgender adults undergoing gender-affirming hormone therapy in Mendoza, Argentina. Eighty-seven participants completed surveys regarding sociodemographic characteristics, lifestyle habits, nutritional counseling, and consumption of cardioprotective foods. We assessed anthropometric indicators and biochemical parameters related to cardiovascular risk. Statistical analyses were performed using GraphPad Prism 8. Data were analyzed using Spearman correlation, the chi-square test, and the Mann-Whitney U test. Results: A high prevalence of modifiable cardiovascular risk factors was identified, including overweight, sedentary behavior, smoking, and low intake of cardioprotective foods. More than half of the participants had never received nutritional counseling. No statistically significant differences were observed between transgender women and transgender men in the evaluated anthropometric and biochemical variables. Nevertheless, significant correlations were identified between body mass index, waist circumference, waist-to-height ratio, and atherogenic lipid markers. Dietary quality showed limited associations with cardiovascular risk indicators, although higher dietary quality was positively associated with HDL cholesterol levels in transgender men. Conclusion: The study highlights the presence of multiple cardiovascular risk factors in transgender individuals receiving gender-affirming hormone therapy and emphasizes the importance of integrating nutritional assessment and cardiometabolic monitoring into comprehensive transgender healthcare. These findings support the need for inclusive nutritional interventions and longitudinal studies addressing cardiovascular health in transgender populations.
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PHYSICOCHEMICAL AND PHYTOTOXIC QUALITY OF IRRIGATION WATER FOR THE TREES OF GENERAL SAN MARTÍN PARK, MENDOZA, ARGENTINA

Background: General San Martín Park, located in Mendoza, Argentina, is the city's most emblematic green infrastructure, designed in 1896 by architect Carlos Thays. The park plays a critical role in microclimate regulation, water conservation, and public health resilience. Aim: The purpose of this study was to assess the quality of the water used for irrigation in the most important park of the city of Mendoza, the General San Martín Park, through a comprehensive series of analyses. Methods: This study assessed the physicochemical and biological quality of irrigation water in the park, focusing on parameters such as temperature, pH, turbidity, electrical conductivity, hardness, alkalinity, nitrates, sulfates, and anthropogenic contaminants. Samples were collected at 20 points across the irrigation network during three periods (October 2024, April 2025, October 2025). Results: Indicate that irrigation water is generally of good quality, suitable for sustaining the park's forest mass. pH values remained within the optimal irrigation range (6.5–8.4), while nitrate levels were consistently below the 30 ppm threshold, with no nitrites detected. Hardness and alkalinity varied spatially, particularly near the Alto Godoy Water Treatment Plant, suggesting localized inputs of dissolved solids. Turbidity and conductivity strongly correlated with hardness, reflecting the influence of suspended and dissolved mineral content from runoff and seasonal hydrological dynamics of the Mendoza River. Importantly, we found no evidence of toxic anthropogenic contaminants such as heavy metals, cyanides, or petroleum derivatives. Discussion: Overall, the findings emphasize the need for continuous monitoring. From a management perspective. These results establish a baseline of water quality indicators for the park. They provide essential input for long-term strategies in conservation, recreation, and environmental education, ensuring resilience against water scarcity and urban expansion. The study underscores the park's role as both a cultural heritage site and a living laboratory for sustainable urban ecology.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Mendoza University - Argentina | Araucária - Scientific Association (leaving).
  • Language of Publication: ENGLISH / PORTUGUESE* / SPANISH**
  • *Year the Journal started accepting manuscripts in Portuguese: 2020
  • *Year the Journal started accepting manuscripts in Spanish: 2026
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 18/09/2026.

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EXPERIMENTAL SUBSTANTIATION OF MANURE FRACTIONATION ON PIG FARMS USING A SPIRAL-SCREW MECHANISM

The main vector of mechanization and automation of livestock farming at the present stage of technological development of producers is the improvement of resource-saving technologies and technical devices that enables agricultural producers to produce relatively expensive and high-quality equipment to improve conditions for the animals. This article was considered a method for effective fractionation of manure on pig farms to further obtain humus for soil fertilization. The optimal conditions for the performance of the presented gadget were identified, namely: the time spent by the manure mass in the rotor is 0.1, with a separation factor of 170 to 180, the partition for the filter is made of metal sheet with holes whose diameter varies from 0.8 to 1.5 mm and a thickness of no more than 1 mm. The device presented in the manuscript has several advantages in the form of automation, low energy consumption and cost, novelty, and high efficiency.
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OPTIMIZATION AND KINETICS STUDIES OF THE DISSOLUTION OF DOLOMITE IN SULPHURIC ACID (H2SO4) VIA BOX-BEHNKEN EXPERIMENTAL DESIGN

Background: The recovery of any valuable component from dolomite as a double carbonate mineral depends on its dissolution efficiency. Aim: This study aimed to optimize and provide a simplified novel approach to the kinetics of dolomite dissolution in sulphuric acid solution using the Box-Behnken experimental design. Methods: The dolomite sample was dissolved in a sulphuric acid solution at seventeen different experimental conditions. The residue containing impurities was removed via filtration, while precipitation was carried out at the optimum conditions. Results and Discussion: The relationship between the independent and dependent variables best fits into the two-factor interaction model with a coefficient of determination of 0.9492, adjusted R² of 0.9187, and predicted R² of 0.7514. The total residual sum of 3x10-13 and adequate precision of 18.769 show that the predicted dissolution efficiency is much closer to the experimental values. The analysis of variance revealed that the individual effect of acid concentration, temperature, and dissolution time all positively contribute to the dissolution. The interactive effect of acid concentration with temperature and the interactive effect of temperature with dissolution time also positively influences the dissolution efficiency. Following the dissolution of dolomite in sulphuric acid, a white precipitate was formed at room temperature, which dissolved back at a temperature of 70 oC, agitation speed of 900 revolutions per minute, and within 10 minutes. A predictive approach using a two-factor interactive model was applied to generate the kinetic data. Conclusions: The established model equation is suitable for predicting dolomite dissolution in sulphuric acid. The application of the shrinking core model to the generated data shows that the reaction between dolomite and sulphuric acid is film diffusion control with a first-order reaction (0.6587) and activation energy of 27.5 KJmol-1k-1.
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TREATMENTS FOR ACUTE LYMPHOBLASTIC LEUKEMIA: A COMPARISON BETWEEN TISAGENLECLEUCEL AND CLOFARABINE

Background: Acute lymphoblastic leukemia (ALL) is a heterogeneous hematological malignancy predominantly affecting individuals under 20 years of age. Traditional chemotherapy, such as clofarabine, has shown efficacy; however, novel immunotherapeutic strategies like tisagenlecleucel (Kymriah®) have significantly altered the treatment paradigm. Aim: This study aimed to perform a comparative analysis of tisagenlecleucel, a CAR-T cell therapy, and clofarabine, a second-generation purine nucleoside analog, evaluating their mechanisms of action, therapeutic benefits, limitations, and clinical applicability across diverse patient populations. Methods: A systematic comparative evaluation was conducted, encompassing pharmacological characteristics, mechanisms of action, treatment protocols, efficacy, safety profiles, and clinical indications of both agents. The analysis considered pharmacokinetic and pharmacodynamic data and included patient demographic variables. Results: Tisagenlecleucel demonstrated high efficacy in refractory B-cell ALL, with durable responses and a blood half-life of 128 days, but with notable immune-related adverse effects such as cytokine release syndrome. Clofarabine, effective across a broader patient population, acts via multiple antitumor mechanisms but carries significant toxicity risks, including infection and sepsis. Discussion: The therapies present distinct clinical profiles: tisagenlecleucel offers targeted immunotherapy with high specificity but requires specialized infrastructure and management of immune toxicities. Clofarabine is more widely accessible and applicable, but is associated with conventional chemotherapy-related side effects. Treatment accessibility and cost differ markedly between the two. Conclusions: Therapy selection should be personalized based on patient-specific factors and institutional resources. Tisagenlecleucel is ideal for pediatric and young adult patients with relapsed/refractory B-cell ALL in CAR-T-capable centers, while clofarabine remains a viable option for broader ALL populations, particularly when genetic therapies are not feasible. Further research is needed to optimize therapeutic strategies and improve access to advanced treatments.
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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