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SEVENTY YEARS OF THE BRAZILIAN FEDERAL COUNCIL OF CHEMISTRY (1956–2026): INSTITUTIONAL TRAJECTORY, PRESIDENCIES, AND PERSPECTIVES FOR THE CHEMISTRY PROFESSION - EN

Background: In 2026, the CFQ/CRQ System turns 70 (Law No. 2,800/1956), overseeing a sector responsible for ~11% of industrial GDP, but it lacked a chronological reconstruction based on its own official primary records. Aim: To reconstruct the System's legal genesis, establish a documented official chronology of its presidencies, and discuss current regulatory challenges. Methods: Historiographical-descriptive documentary research based on normative sources and unprecedented access to the internal record "Galeria de Presidentes," provided by the CFQ Presidency Office in 2026. Results: Eight substantive presidencies and interim periods (1957–2026) were detailed, substantiating the interim exercise by Oscar Bergstron Lourenço (1963–1964) and Juvenal Dória's inauguration in 1964. The System now comprises 21 regional councils and over 230,000 registrants. The study identified under-documentation of Hebe Martelli's trajectory (the only female president) and an open divergence regarding the number of regional councils created in 1957. Discussion: Normative Resolution No. 36/1974 remains the milestone for professional attributions. Recent regulations revisit historical challenges, such as attributing competencies to hybrid curricula and establishing chemical safety as a public good, requiring anticipation of energy, materials, and digital transitions. Limitations: The chronology relies on institutional records that the authors did not independently audit against primary archives. Conclusions: Access to primary records consolidated the documentary memory of the System's seventy years, whose legacy lies in adapting the regulatory framework to technological transformations.
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CHARACTERIZATION OF TICKS IN THE GRAN MENDOZA AREA, MENDOZA, ARGENTINA

Background: Vector-borne diseases are increasingly important because they are emerging and re-emerging. Of the 867 tick species reported worldwide, 10% (86 species) have public health implications; 58 parasitize dogs, and 12 have been documented in Argentina. Tick-borne agents are increasingly relevant in the Cuyo region, with implications for both public health and domestic animal health. In Mendoza, the Rhipicephalus sanguineus complex and Amblyomma tigrinum have been documented. Aim: This study aimed to determine whether one tick genus predominated over the other, compared with previous studies in the region. Methods: We collected ticks from dogs attending municipal vaccination campaigns and veterinary clinics in several departments of the Greater Mendoza area (Ciudad/Capital, Luján de Cuyo, Godoy Cruz, and Guaymallén). Specimens were preserved in 70% (v/v) ethanol in sealed containers until analysis. Identification was performed using a stereomicroscope and the taxonomic keys of Nava. Results: The highest number of ticks was obtained from Ciudad/Capital, followed by Luján de Cuyo, Godoy Cruz, and Guaymallén. A total of 439 specimens were collected and classified by genus, species, and sex. Of these, 94.46% (415 ticks) corresponded to the Rhipicephalus sanguineus complex, including 193 females (43.96%) and 222 males (50.5%). The remaining 5.48% (24 ticks) were identified as Amblyomma tigrinum, including 17 females (3.89%) and 7 males (1.59%). Discussion: These findings confirm the marked predominance of the Rhipicephalus sanguineus complex among ticks collected from dogs in the Greater Mendoza area.
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PHYSICOCHEMICAL AND PHYTOTOXIC QUALITY OF IRRIGATION WATER FOR THE TREES OF GENERAL SAN MARTÍN PARK, MENDOZA, ARGENTINA

Background: General San Martín Park, located in Mendoza, Argentina, is the city's most emblematic green infrastructure, designed in 1896 by architect Carlos Thays. The park plays a critical role in microclimate regulation, water conservation, and public health resilience. Aim: The purpose of this study was to assess the quality of the water used for irrigation in the most important park of the city of Mendoza, the General San Martín Park, through a comprehensive series of analyses. Methods: This study assessed the physicochemical and biological quality of irrigation water in the park, focusing on parameters such as temperature, pH, turbidity, electrical conductivity, hardness, alkalinity, nitrates, sulfates, and anthropogenic contaminants. Samples were collected at 20 points across the irrigation network during three periods (October 2024, April 2025, October 2025). Results: Indicate that irrigation water is generally of good quality, suitable for sustaining the park's forest mass. pH values remained within the optimal irrigation range (6.5–8.4), while nitrate levels were consistently below the 30 ppm threshold, with no nitrites detected. Hardness and alkalinity varied spatially, particularly near the Alto Godoy Water Treatment Plant, suggesting localized inputs of dissolved solids. Turbidity and conductivity strongly correlated with hardness, reflecting the influence of suspended and dissolved mineral content from runoff and seasonal hydrological dynamics of the Mendoza River. Importantly, we found no evidence of toxic anthropogenic contaminants such as heavy metals, cyanides, or petroleum derivatives. Discussion: Overall, the findings emphasize the need for continuous monitoring. From a management perspective. These results establish a baseline of water quality indicators for the park. They provide essential input for long-term strategies in conservation, recreation, and environmental education, ensuring resilience against water scarcity and urban expansion. The study underscores the park's role as both a cultural heritage site and a living laboratory for sustainable urban ecology.
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General information

SOUTHERN JOURNAL OF SCIENCES

    General information about this journal
  • Title: SOUTHERN JOURNAL OF SCIENCES
  • Short Title: South. J. Sci.
  • ISSN: 2764-5959 (Online); ISSN: 2764-5967 (Print)
  • Universal Decimal Classification (UDC): 001
  • Review Process: Double-Blind Peer-Review
  • Accessibility: Platinum Open Access, NO-APCs.
  • Digital preservation: Portico
  • Frequency of Publication: biannual [2 issues per year]. Journal publication schedule
  • DOI: 10.48141/2764-5959
  • Website: https://www.sjofsciences.com/
  • Country: BRAZIL
  • Publisher: Mendoza University - Argentina | Araucária - Scientific Association (leaving).
  • Language of Publication: ENGLISH / PORTUGUESE* / SPANISH**
  • *Year the Journal started accepting manuscripts in Portuguese: 2020
  • *Year the Journal started accepting manuscripts in Spanish: 2026
  • First issue year: 1993
  • Free full text: Yes
  • Indexed in: Index Copernicus; Latindex, and I2OR.
  • Formerly known as the Southern Brazilian Journal of Chemistry (1993 to 2021).
  • Former ISSN: 2674-6891 (Online); Former ISSN: 0104-5431 (Print).
  • Website last update: 18/09/2026.

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EVALUATION OF IMMUNE SYSTEM STIMULATION WITH VACCINE PREPARED AGAINST INDUCED BREAST CANCER IN ALBINO MICE

This study was designed to prepare vaccines. Cancer vaccines promote the destruction of cancer cells,and the cancer cells contain special antigens on their surface when the vaccine is given, it acts as an antigen to activate the immune system. The IL-2 stimulates the response to a type of cells called T-cell, and outer membrane vesicle (OMV) targeting cancer cells by stimulating the immunity to respond with it two types including innate andadaptive immunity, that lead to stimulating the immune system to reduce mammary adenocarcinoma induction in lab mice using T4-1 cell line breast cancer by taking blood and serum to evaluate the immune system efficacy. The tumor induction success by monitoring mice body weight loss showed the lost weight began in the third week after tumor induction, so 23.2 g at first and second week to 14.35 g at the end of the fourth week, whereas the control animals were weighed 32.37 g. The immunity system efficacy results appear a difference in blood and serum parameters after cancer induction. The result shows an increase in total WBC and monocytes (5900, 0.2 cells/mm respectively) but non significantly decreased in neutrophils and lymphocytes count (2.6, 5.9 cells/mm, respectively). Therefore, the first and second doses of vaccines increased the antibody and complement of the immune system compared with control. While Eliaza data for cytokines profile referred to elevated IL2 (26.5 pg/ml)in the serum of vaccination mice but only significantly decreased in IL6 and IL-22 amount (20.4 and 19.6 pg/ml respectively) comparing with control.
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ASSESSMENT OF SERUM SCLEROSTIN LEVEL AS A BIOMARKER ASSOCIATED WITH BONE DISORDERS IN Β-THALASSEMIA PATIENTS IN AL- NAJAF CITY, IRAQ

Background: β-thalassemia is a blood disorder in which the body does not make hemoglobin normally. Aim: To assess serum sclerostin in female patients with beta-thalassemia and compare with the healthy controls and to predict its complication associated with the bone pathophysiology, for designed improvement the lifestyle goodliness for these patients. Material and methods: Sixty-nine female beta-thalassemia (βT) patients (54 βT major and 15 βT Intermedia), aged 8-40 years who dependent on transfused blood, and 20 healthy controls were evaluated serum sclerostin, and was examined the relationship with hematological parameters RBC, Hb, PCV, WBC, PLT, BMI, splenic status, iron, and ferritin levels. The information of beta-thalassemia patients was collected and records by the questioner. Results: A significantly increased serum sclerostin level (mean 26.80±0.91) pg/ml was showed in βT patients compared with the healthy controls (10.03±0.68, p  smaller than  0.001) pg/ml. Furthermore, a significant decrease (p smaller than 0.05) of the sclerostin level was observed in β-thalassemia major compared to intermedia β-thalassemia patients. Serum sclerostin level revealed a significant increase in progress age; it is highest in the age group (30-40) year as compared with age group (8-18) and (19-29) year respectively. Sclerostin showed no associations with the RBC, Hb, PCV, and significantly positively correlated (p smaller than 0.05) with serum iron, ferritin levels, WBC, and PLT count. Significantly higher sclerostin levels in splenectomized and underweight groups were observed compared to unsplenectomized and normal-weight groups (p smaller than 0.05) of βT patients. Conclusions: Sclerostin plays an important role in beta-thalassemia patients and can serve as a biomarker associated with the bone pathophysiology and indicator to prevent the continuation of such serious diseases caused by iron overload in these patients.
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D-DIMER A RISK FACTOR ASSOCIATED WITH C-REACTIVE PROTEIN FOR PREDICTING THE SEVERITY OF INFECTION BY COVID-19

Background: COVID-19, caused by SARS-CoV-2, has unresolved mortality risk factors and clinical course, highlighting the need for further research. Aims: The study aimed to asses D-dimer and C-Reactive Protein (CRP) as the risk factors for severity covid-19 and who are less capable of surviving. Methods: A retrospective study conduct of COVID-19 in adult inpatients aged >20 at Al-sadder and Alamal Hospital in Iraq. Demographics, clinical trials, treatments, and viral RNA samples were analyzed. The study involved 100 patients, with 67 discharged and 33 hospitalized died. The majority of the participants 45% were aged < 40, but 55% were aged >40 years. Results: A significant and 57% were male 37(55.2%) Survivor vs. 20 (60.6%) non-survivor, p=0.024), more than 43% were female (30(44.8%) Survivor vs. 13(39.4%) non-survivor, p=0.010. Patients had underlying comorbidities (66%), survivor 37(55%), and non-survivor 29(87%). The most prominent comorbidity in non-survivors more than survivors was diabetic mellitus 85%, asthma 58%, stroke 48%, renal failure 42%, heart strake 33%, and hypertension 18%. The study found significant differences in WBC, lymphocyte count, D-dimer, Ferritin, CRP, and LDH levels in non-survivors compared to survivor patients, with a positive correlation between D- dimer and these parameters. The ROC analysis curve showed CRP with a high AUC of 80.2%, 87.9% sensitivity, and 37.3% specificity, while D-dimer and LDH had AUCs of 0.74.9 and 70%, respectively. Discussion: The study found that older age, higher d-dimer, ferritin, CRP, and LDH are associated with disease severity and higher mortality risk in adult COVID-19 patients. Conclusions: These biomarkers could aid in early detection of disease progression signs and better patient management
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SOUTHERN JOURNAL OF SCIENCES

The SOUTHERN JOURNAL OF SCIENCES publishes articles in Chemistry, Physics, Mathematics, Biology, Pharmacy, Medicine, Engineering, Industrial Science, Agriculture, and related interdisciplinary areas and is intended to fill a gap in terms of scientific information worldwide. All manuscripts can be published either in English or Portuguese, with tile, abstracts, and keywords in English. At present, there are NO PUBLICATION FEES. Editors will cover web hosting, open access, DOI number, and other service costs.

We have set high standards for the articles to be published by ensuring strong but fair refereeing by at least two reviewers. We hope that this Journal will provide a forum for disseminating high-quality research in chemistry and related areas and are open to any questions and suggestions. Starting in 2020, the SOUTHERN JOURNAL OF SCIENCES will have two issues per year (June and December).

Thank you very much for choosing the SOUTHERN JOURNAL OF SCIENCES to publish your paper!
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