SOUTHERN JOURNAL OF SCIENCES

The article reviews the chemical composition of borehole and surface waters in three villages of one of the regions of Georgia - Kakheti, Gurjaani Municipality. The study was specifically focused on iodine content in waters. It turned out that certain amount of iodine really existed in borehole waters, which means that by everyday drinking of water, the human body gets maybe not the complete required amount of iodine, but at least some part of it. It was also discovered, that according to certain parameters, waters are clean, do not contain heavy metals and can be freely used for drinking and cooking. The chemical composition of the Alazani River was also examined according to all four seasons. This river is interesting because of being used for irrigation of vineyards and fruit gardens.

The trypsin-like activity of mixed saliva in orthopedic patients after implant placement was monitored. Proved negative impact on the processes of repair of background somatic pathology (peptic ulcers and 12 duodenal ulcers), justify the application of immunomodulator "Erbisol" as a drug that speeds up the repair processes during implantation. At present, the relevant issues are those related to the development of inflammatory complications at the stage of rehabilitation of patients, especially in the presence of somatic pathology and the study of the tissue complex of the implantation zone. Peptic ulcer disease occupies one of the main places in the structure of lesions of the digestive system. The close interdependence between the pathology of internal organs and the oral cavity is confirmed by numerous observations and studies.Implant placement is accompanied by changes in the enzymatic activity of mixed saliva. The presence of somatic pathology (ulcerative disease of the stomach and 12 duodenal ulcers) often leads to more long-term violations of the enzymatic activity of saliva. The use of the drug "Erbisol" in orthopedic dentistry accelerates the repair process, as evidenced by the earlier periods of normalization of the enzymatic activity of mixed saliva, after the installation of implants.Regular and timely monitoring of the condition of the periarticular tissues, as well as objective diagnosis of early inflammatory complications, are necessary to ensure the reliability and long-term functioning of prosthetic structures installed on implants in the oral cavity.It can be concluded that the purpose of our study was to study the trypsin-like activity (TPA) of mixed saliva after implant placement on the background of somatic pathology.

Background: Diabetes Type 2 is a complex disorder described by an imbalance between insulin resistance and secretion that induce liver glucose output. It has been shown that serum insulin levels are affected by a sperm plasma membrane and acrosome. Therefore, during insulin resistance spermatogenesis changes, diabetic patients detect testicular changes. Aims: This research aims to know the effect of diabetic type 2 on some aspects of fertility in men by studying the characteristics of the semen and some biochemical parameters in seminal plasma. Methods: This study was achieved at the Center for Endocrinology and Diabetes Specialists in Maysan province from February to November 2018 and included 45 men (30 diabetic and 15 healthy in the control group) aged 30 to 59 years. The patients were divided according to age into two groups, the first (30-39) and second (40-59) years, also divided by the duration of diabetes into two groups, the first (1-5) and second (6-10) year. Results: The pH of semen in the second age group (40-49 years) group and first duration (1-5 years) group were significantly decreased (P <0.05) in diabetes compared with the control group. Volume and viscosity did not have significant differences in patients compared to the control following the age and duration of diabetes. Liquefaction only in the first age (30-39 years) group significantly increased (P <0.05) compared to the control. The concentration of sperm, progressive motility, non-progressive and normal morphology decreased (P <0.05) significantly. While the sluggish, dead, and abnormal morphology significantly increased (P <0.05) in all diabetes groups compared with the control. The fructose and alkaline phosphatase values in the seminal plasma were not differing significantly in patients compared with the control. Zinc and glutathione values decreased significantly (P <0.05) compared with control in each age and duration of diabetes. Discussion: Insulin stimulates the Ledying cell function, defect insulin effect on spermatogenesis. Impaired sperm motility in a patient with D.M. might be attributed to many reasons, such as increased ROS level, altered mitochondria DNA, and decreased epididymal products. Conclusion: our measurement indicates that there is an effect of type 2 diabetes mellitus on semen parameters and seminal plasma biochemical parameters.